Cuquío is a town municipality of the state of Jalisco located in the central region of the state of Jalisco. Although culturally and traditionally part of the region of the Highlands. It limits to the north with the municipality of Yahualica and the State of Zacatecas. To the south, Zapotlanejo and Acatic. To the east, Yahualica and Tepatitlán. And to the west, Ixtlahuacán del Río. Cuquío is located at the center-northeast of the State, at coordinates 20°55'6 '' north latitude and 103°01'3 '' west longitude, at a height of 1,810 meters above sea level. It was the Purépechas who repeatedly entered these valleys after the Guerra del Salitre.
The tribe of the coquías settled in the Brotherhood, to 2 kilometers of the present town, of whose name it is conjectured that the denomination comes to him. He also depended on the Tonalteca kingdom.