The Department San Ignacio is located in the west of the province of Misiones, Argentina. It limits with the departments of Libertador General San Martin, Cainguás, Oberá, Candelaria and the Republic of Paraguay. The department has 1,607 km², equivalent to 5.4% of the province's total. Its population is 57,728 inhabitants. The name of this district is reminiscent of Saint Ignatius of Loyola, founder of the Society of Jesus, a Catholic institution that maintained wide influence in the area for approximately two centuries. Its main economic activities are related to the agricultural crop, especially yerba mate, tea, manioc, pineapple, citrus and other horticultural products, as well as various logging ventures.
As for tourism, in this department is the town of San Ignacio, the second most visited town in the province. In it rest the remains of the reduction of San Ignacio Miní, maximum expression of the Jesuit-Guaraní culture. Along with the vestiges of Our Lady of Santa Ana, Santa Maria La Mayor and Our Lady of Loreto, forms the so-called "Circuit of Reductions". Although its departmental capital is the historic town of San Ignacio, the town with the largest number of inhabitants is Jardín América. Because of its rich history, another important town is Corpus, once the capital of the National Territory of Misiones.